Saifuddin Nasution Ismail

In January 2010, Saifuddin was appointed the Secretary-General of PKR, replacing Salehuddin Hashim. In 2014 he vacated the post to run for the party's deputy presidency, but was defeated by Azmin Ali. He was once again appointed to the post of PKR Secretary-General in November 2016, this time to replace Rafizi Ramli.

Saifuddin was initially a member of the youth wing of the ruling UMNO party but was expelled in 1999 as its assistant secretary. An ally of Anwar Ibrahim, Saifuddin then defected to the opposition KeADILan party, which later became PKR.

Saifuddin election debut was in the 1999 general election contesting the seat of Padang Serai, Kedah for PKR but lost. A year later, he won the Kedah State Assembly seat of Lunas in a 2000 by-election. However he failed in his bid to be elevated to the federal Parliament in the 2004 election, losing to Lim Bee Kau of the Barisan Nasional in the seat of Padang Serai again. In the 2008 election, Saifuddin contested and won the federal seat of Machang in Kelantan. For the 2013 election he returned to Kedah to contest the seat of Kulim-Bandar Baharu, but was defeated by UMNO's Abd. Aziz Sheikh Fadzir. Somehow in 2018 election Saifuddin made a comeback to win both the Kulim-Bandar Baharu parliamentary seat and Pantai Jerejak, Penang state seat.

Datuk Seri Saifuddin Nasution bin Ismail (Jawi: سيف الدين ناسوتيون بن اسماعيل; born 7 December 1963) is a Malaysian politician. He is the former Minister of Domestic Trade and Consumer Affairs, Member of Parliament (MP) for the Kulim-Bandar Baharu constituency in Kedah and also Penang State Legislative Assemblyman for Pantai Jerejak concurrently. He is a senior figure in the People's Justice Party (PKR), in the Pakatan Harapan (PH) coalition. He is also the former MP for the Machang constituency in Kelantan from 2008 to 2013.