Age, Biography and Wiki
Jacques Neefjes was born on 8 December, 1959 in Dutch, is a Dutch biochemist. Discover Jacques Neefjes's Biography, Age, Height, Physical Stats, Dating/Affairs, Family and career updates. Learn How rich is He in this year and how He spends money? Also learn how He earned most of networth at the age of 61 years old?
|Age||61 years old|
|Born||8 December 1959|
We recommend you to check the complete list of Famous People born on 8 December. He is a member of famous with the age 61 years old group.
Jacques Neefjes Height, Weight & Measurements
At 61 years old, Jacques Neefjes height not available right now. We will update Jacques Neefjes's Height, weight, Body Measurements, Eye Color, Hair Color, Shoe & Dress size soon as possible.
|Body Measurements||Not Available|
|Eye Color||Not Available|
|Hair Color||Not Available|
Dating & Relationship status
He is currently single. He is not dating anyone. We don't have much information about He's past relationship and any previous engaged. According to our Database, He has no children.
Jacques Neefjes Net Worth
He net worth has been growing significantly in 2018-19. So, how much is Jacques Neefjes worth at the age of 61 years old? Jacques Neefjes’s income source is mostly from being a successful . He is from Dutch. We have estimated Jacques Neefjes's net worth, money, salary, income, and assets.
|Net Worth in 2020||$1 Million - $5 Million|
|Salary in 2019||Under Review|
|Net Worth in 2019||Pending|
|Salary in 2019||Under Review|
|Source of Income|
Jacques Neefjes Social Network
|Wikipedia||Jacques Neefjes Wikipedia|
During his career, Jacques Neefjes has authored more than 280 scientific publications reaching more than 30,000 citations. Neefjes’ discoveries on antigen presentation by the class I and II major histocompatibility complexes (MHC) constitute today's textbook knowledge. Through his exploration of the cell biology of the MHC, Jacques Neefjes became an expert on endocytosis and intracellular transport. In 2017, Neefjes and his team made fundamental discoveries regarding endosome positioning by the endoplasmic reticulum. Neefjes further expanded his work on endosomes to phagosomes and intracellular bacteria. By combining chemistry, cell biology and biochemistry with genetic screens, Neefjes identified inhibitors to disturb bacterial survival strategies, representing one of the first antibiotics acting by targeting the host, rather than the pathogen. In 2015, Neefjes has demonstrated that Salmonella infection promote cancer development. Since 2019, Jacques Neefjes is co-financing the production of a promising cancer drug, Aclarubicin, which disappeared from the European market at the beginning of the 21st century.
Since 2016, he is head of the Cell and Chemical Biology department at the Leiden University Medical Center (the Netherlands).
An ER-Associated Pathway Defines Endosomal Architecture for Controlled Cargo Transport. Jongsma ML, Berlin I, Wijdeven RH, Janssen L, Janssen GM, Garstka MA, Janssen H, Mensink M, van Veelen PA, Spaapen RM, and Neefjes JJ. Cell. 2016. 166:152-166
Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1. Kuijl C, Savage ND, Marsman M, Tuin AW, Janssen L, Egan DA, Ketema M, Van Den Nieuwendijk R, Van Den Eeden SJ, Geluk A, Poot A, Van Der Marel G, Beijersbergen RL, Overkleeft H, Ottenhoff TH, and Neefjes JJ. Nature. 2007. 450:725–730
The major substrates for TAP in vivo are derived from newly synthesized proteins. Reits EA, Vos JC, Grommé M, and Neefjes JJ. Nature. 2000. 404:774–778.
After his Ph.D., Jacques Neefjes did two post-doctoral visits. First, from 1991 to 1992, he visited the laboratory of Drs Benoit and Mathis at the Institut de Chimie Biologique, Strasbourg (France). Then, he obtained a 2-year fellowship from the European Molecular Biology Organization (EMBO) to visit the laboratory of Prof. Dr. Hämmerling at the German Cancer Research Center (DKFZ), in Heidelberg (Germany) from 1992 to 1993. In 1993, Jacques Neefjes became a staff member of the Division of Cellular Biochemistry at the NKI. In 1998, he became head of the division of Tumor Biology. From 1999 to 2016, he occupied the position of "Extraordinary professor" at the Leiden University. He was the Dean of the Graduate School Oncology Amsterdam (OOA) from 2000 to 2003.
The Biosynthetic Pathway of MHC Class II but Not Class I Molecules Intersects the Endocytic Route. Neefjes JJ, Stollorx V, Peters PJ, Geuze HJ, and Ploegh HL. Cell. 1990. 61:171-183.
From 1979 to 1985, Jacques Neefjes studied Chemistry at the Vrije Universiteit Amsterdam. Then, he performed his Ph.D. studies at the Division of Cellular Biochemistry, in the Netherlands Cancer Institute (NKI) under the supervision of Prof. Dr. Ploegh in Amsterdam. During his thesis, he investigated the Cell Biological Aspect of MHC class I and II molecules. He obtained his Ph.D. degree on the 2nd of November 1990 with Cum Laude.
Jacques (Sjaak) Neefjes (born 8 December 1959), is a Dutch scientist who made breakthroughs in several research disciplines such as immunology, cell biology, chemistry, cancer biology, microbiology, and epidemiology. He is a professor at the Leiden University Medical Center.